MF266-1

CAT: 0804-HY-111304Size: 1 EachDry Ice: NoHazardous: No

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CAT#:0804-HY-111304Size:1 Each

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Description

MF266-1 is a selective E prostanoid receptor 1 (EP1) antagonist with an Ki value of 3.8 nM. MF266-1 also has moderate selectivity for thromboxane A2 receptor (TP) . MF266-1 is promising for research of arthritis[1].

CAS Number

848188-18-1

UNSPSC

12352005

Target

Prostaglandin Receptor; Thrombopoietin Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Immunology/Inflammation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/mf266-1.html

Smiles

FC(F)(C(O)(C1=CN=CC(C2=C(C3=CC(Cl)=CC=C3OCC4=CC=CC=C4)C=CS2)=C1)O)F

Molecular Formula

C24H17ClF3NO3S

Molecular Weight

491.91

References & Citations

[1]Clark P, et al. MF498 [N-{[4- (5,9-Diethoxy-6-oxo-6,8-dihydro-7H-pyrrolo[3,4-g]quinolin-7-yl) -3-methylbenzyl]sulfonyl}-2- (2-methoxyphenyl) acetamide], a selective E prostanoid receptor 4 antagonist, relieves joint inflammation and pain in rodent models of rheumatoid and osteoarthritis. J Pharmacol Exp Ther. 2008 May;325 (2) :425-34.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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MF266-1

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