Biotinylated Human DPPIV Protein, His,Avitag™ (active enzyme)

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Biotinylated Human DPPIV Protein, His,Avitag™ (active enzyme)

CAT:

716-DP4-H82E4-100ug

Size:

100 µg

Price:

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Biotinylated Human DPPIV Protein, His,Avitag™ (active enzyme)

Background: Dipeptidyl peptidase-IV (DPPIV) is also known as adenosine deaminase complexing protein 2, DPPIV or CD26 is antigenic enzyme expressed on the surface of most cell types and is associated with immune regulation, signal transduction and apoptosis. It is an intrinsic membrane glycoprotein and a serine exopeptidase that cleaves X-proline dipeptides from the N-terminus of polypeptides. The substrates of DPPIV are proline (or alanine)-containing peptides and include growth factors, chemokines, neuropeptides, and vasoactive peptides. DPPIV plays a major role in glucose metabolism. It is responsible for the degradation of incretins such as GLP-1. DPPIV plays an important role in tumor biology, and is useful as a marker for various cancers, with its levels either on the cell surface or in the serum increased in some neoplasms and decreased in others. DPPIV also binds the enzyme adenosine deaminase specifically and with high affinity. The significance of this interaction has yet to be established.
Description: Biotinylated Human DPPIV Protein, His,Avitag (DP4-H82E4) is expressed from human 293 cells (HEK293). It contains AA Asp 34 - Pro 766 (Accession # NP_001926.2).
Specifications: This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™). The protein has a calculated MW of 88.4 kDa. The protein migrates as 95-120 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Expression Region: Asp 34 - Pro 766
Host: HEK 293
Target: DPPIV
Conjugation: Biotin-labeled
Tag: C-10×His & C-Avi
Source: Human
Stability: -20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Endotoxin: 1.0 EU per μg
Purity: 95%
Bioactivity: Immobilized MERS S1 protein, His Tag (Cat. No. S1N-M52H5) at 2 μg/mL (100 μL/well) can bind Biotinylated Human DPPIV Protein, His,Avitag (Cat. No. DP4-H82E4) with a linear range of 0.8-6 ng/mL (QC tested).
Format: Powder
Buffer: PBS, pH7.4
Additives: Trehalose
Molecular Weight: 88.4 kDa
Shipping Conditions: Room Temperature
Storage Conditions: -20°C

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Each item in our collection, is tested for precision and quality, ensuring dependable solutions for your research. As we continue to incorporate the latest advancements, Gentaur ensures that our product range remains relevant and versatile, providing you with the tools needed for both current and future projects.

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