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ADAM10 antibody

CAT: 0710-FNab10875Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab10875Size:100 µg
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Synonyms
Disintegrin and metalloproteinase domain-containing protein 10 (ADAM 10) |CDw156|Kuzbanian protein homolog|Mammalian disintegrin-metalloprotease|ADAM10|KUZ|MADM
Gene ID
102
UniProt
O14672
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
ADAM metallopeptidase domain 10
Target
ADAM10
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
90 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB

UniProtKB · O14672

Disintegrin and metalloproteinase domain-containing protein 10

ADA10_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
O14672
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
ADAM10
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
ADAM 10
EC number
3.4.24.81
Processing
Precursor
Secondary accessions
B4DU28, Q10742, Q92650
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Disease

Alzheimer diseaseAmyloidosisDisease variantNeurodegeneration

Cellular component

Cell junctionCell membraneCell projectionCytoplasmCytoplasmic vesicleGolgi apparatusMembrane

PTM

Cleavage on pair of basic residuesDisulfide bondGlycoproteinPhosphoproteinZymogen

Molecular function

HydrolaseMetalloproteaseProtease

Ligand

Metal-bindingZinc

Biological process

Notch signaling pathway

Domain

SH3-bindingSignalTransmembraneTransmembrane helix