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Procyanidol B4

CAT: 0804-HY-107208-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-107208-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Procyanidol B4 ((-) -Procyanidin B4) is an orally active polyphenol found in Q.gilva. Procyanidol B4 exerts antioxidant activity by scavenging DPPH (IC50: 12.15 μM) and Nitro blue tetrazolium chloride (NBT) (HY-15925) (IC50: 8.67 μM). Procyanidol B4 exhibits anti-inflammatory activity by inhibiting the expression of COX-2 and IL-1β and iNOS[1][2].
CAS Number
29106-51-2
Product Name Alternative
(-) -Procyanidin B4
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
COX; Interleukin Related; NO Synthase; Reactive Oxygen Species (ROS)
Type
Natural Products
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/procyanidol-b4.html
Purity
99.89
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O[C@H]1[C@H](C2=C3C(C[C@@H](O)[C@@H](C4=CC(O)=C(O)C=C4)O3)=C(O)C=C2O)C5=C(O)C=C(O)C=C5O[C@@H]1C6=CC(O)=C(O)C=C6
Molecular Formula
C30H26O12
Molecular Weight
578.52
Precautions
H302, H315, H319, H335
References & Citations
[1]Youn SH, et al. Anti-Inflammatory and Anti-Urolithiasis Effects of Polyphenolic Compounds from Quercus gilva Blume. Molecules. 2017 Jul 5;22 (7) :1121.|[2]Bittner K, et al. Systemic absorption and metabolism of dietary procyanidin B4 in pigs. Mol Nutr Food Res. 2014 Dec;58 (12) :2261-73.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Natural Products
Clinical Information
No Development Reported

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