Products for Research Use Only
RegisterLogin

HS-243

CAT: 0804-HY-134911-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-134911-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
HS-243 is a potent and selective IRAK-4 and IRAK-1 inhibitor, with IC50 values of 20 and 24 nM. HS-243 shows minimal TAK1 (transforming growth factor β-activated kinase 1) inhibition activity, with a IC50 of 0.5 μM. HS-243 shows anti-inflammatory and anticancer activity[1].
CAS Number
848249-10-5
UNSPSC
12352005
Hazard Statement
H302, H315, H319
Target
CDK; IRAK
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Immunology/Inflammation
Applications
COVID-19-anti-virus
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/hs-243.html
Purity
99.95
Solubility
DMSO : 41.67 mg/mL (ultrasonic)
Smiles
O=C(NC1=NC2=CC=CC=C2N1CCC)C3=CC=CC([N+]([O-])=O)=C3
Molecular Formula
C17H16N4O3
Molecular Weight
324.33
Precautions
H302, H315, H319
References & Citations
[1]Scarneo SA, et al. A highly selective inhibitor of interleukin-1 receptor-associated kinases 1/4 (IRAK-1/4) delineates the distinct signaling roles of IRAK-1/4 and the TAK1 kinase. J Biol Chem. 2020 Feb 7;295 (6) :1565-1574.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CLK; IRAK1; IRAK4

Related Products

CatalogName
HY-100487-01TAK-243
HY-113857RAD-243
HY-155470IMP 243
HY-W999572CRBN ligand-243
HY-168042Antibacterial agent 243
HY-100487RTAK-243 (Standard)
HY-114514R 47 243
HY-106094CY 208-243
HY-129156-01HS-1793
HY-122878HS-131

Alternative Products

CatalogName
BA3795-25HS-243
A22071-25HS-243 25mg
A22071-5HS-243 5mg
A22071-50HS-243 50mg
A22071-1HS-243 1mg
A22071-100HS-243 100mg
A22071-10HS-243 10mg
BA2722-5TAK-243
C4813-10ML-243
TRC-H673510-100MGHU 243

Popular Products