Azido-PEG5-amine

• Description :

  Azido-PEG5-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG5-amine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

• UNSPSC :

  12352211

• Hazard Statement :

  H314

• Target :

  PROTAC Linkers

• Type :

  Reference compound

• Related Pathways :

  PROTAC

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/azido-peg5-amine.html

• Purity :

  98.0

• Solubility :

  10 mM in DMSO

• Smiles :

  NCCOCCOCCOCCOCCOCCN=[N+]=[N-]

• Molecular Formula :

  C12H26N4O5

• Molecular Weight :

  306.36

• Precautions :

  H314

• References & Citations :

  [1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  4°C (Powder, protect from light)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  PEG Linkers

• CAS Number :

  [516493-93-9]