CPTH2-Alkyne

• UNSPSC Description:

  CPTH2-Alkyne is a cell active analog of CPTH2 (HY-W013274). CPTH2-Alkyne specifically accumulates in nucleoli and locates in nuclear periphery and in cytoplasma. CPTH2-Alkyne inhibits N-acetyltransferase 10 (NAT10). CPTH2-Alkyne is used in study of nuclear architecture and application in laminopathy[1].

• Target Antigen:

  Histone Acetyltransferase

• Type:

  Reference compound

• Related Pathways:

  Epigenetics

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/cpth2-alkyne.html

• Solubility:

  10 mM in DMSO

• Smiles:

  ClC1=CC=C(C2=CSC(N(CC#C)/N=C3CCCC\3)=N2)C=C1

• Molecular Weight:

  329.85

• References & Citations:

  [1]Larrieu D, et al., Chemical inhibition of NAT10 corrects defects of laminopathic cells. Science. 2014 May 2;344(6183):527-32.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  1613116-16-7