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Nitrendipine (Standard)

CAT: 0804-HY-B0424R-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B0424R-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Nitrendipine (Standard) is the analytical standard of Nitrendipine. This product is intended for research and analytical applications. Nitrendipine (BAY-E-5009) is an orally active analog of Nifedipine (HY-B0284) and dihydropyridine calcium channel blocker. Nitrendipine induces Apoptosis. Nitrendipine has antihypertensive effects. Nitrendipine blocks alcohol and Morphine withdrawal symptoms. Nitrendipine reduces right ventricular hypertrophy and pulmonary vascular changes induced by intermittent hypoxia. Nitrendipine has anticancer effects on neuroblastoma[1][2][3][4][5][6][7][8][9][10][11].
CAS Number
39562-70-4
Product Name Alternative
BAY-E-5009 (Standard)
UNSPSC
12352005
Hazard Statement
H312-H332-H362
Target
Apoptosis; Calcium Channel; Reference Standards
Type
Reference Standards
Related Pathways
Apoptosis; Membrane Transporter/Ion Channel; Neuronal Signaling; Others
Field of Research
Cancer; Neurological Disease; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/nitrendipine-standard.html
Smiles
O=C(C1=C(C)NC(C)=C(C(OC)=O)C1C2=CC=CC([N+]([O-])=O)=C2)OCC
Molecular Formula
C18H20N2O6
Molecular Weight
360.36
Precautions
P260-P261-P263-P264-P270-P271-P280-P302+P352-P304+P340-P362+P364-P501
References & Citations
[1]Bellemann, P., et al., [3H]-Nitrendipine, a potent calcium antagonist, binds with high affinity to cardiac membranes. Arzneimittelforschung, 1981. 31 (12) : p. 2064-7.|[2]S Kazda, et al. Diuretic effect of nitrendipine contributes to its antihypertensive efficacy: a review. J Cardiovasc Pharmacol. 1988;12 Suppl 4:S1-5.|[3]He-Hui Xie, et al. Synergism of atenolol and nitrendipine on hemodynamic amelioration and organ protection in hypertensive rats. J Hypertens. 2005 Jan;23 (1) :193-201.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

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