Uridine

• Description :

  Uridine (β-Uridine) is a nucleoside compound composed of uracil and a ribose ring, which are connected by a β-N1-glycosidic bond[1].

• CAS Number :

  [58-96-8]

• Product Name Alternative :

  β-Uridine

• UNSPSC :

  12352005

• Hazard Statement :

  H302, H315, H319, H335

• Target :

  Endogenous Metabolite; NF-κB; Nucleoside Antimetabolite/Analog

• Type :

  Natural Products

• Related Pathways :

  Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; NF-κB

• Applications :

  Metabolism-protein/nucleotide metabolism

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/Uridin.html

• Purity :

  99.98

• Solubility :

  DMSO : 50 mg/mL (ultrasonic) |H2O : ≥ 100 mg/mL

• Smiles :

  O[C@H]1[C@@H](O)[C@H](N2C(NC(C=C2)=O)=O)O[C@@H]1CO

• Molecular Formula :

  C9H12N2O6

• Molecular Weight :

  244.20

• Precautions :

  H302, H315, H319, H335

• References & Citations :

  [1]Sokoloski JA, et al., Effects of uridine on the growth and differentiation of HL-60 leukemia cells. Leuk Res. 1991;15 (11) :1051-8. |[2]Zheng WV, et al., Uridine alleviates carbon tetrachloride-induced liver fibrosis by regulating the activity of liver-related cells. J Cell Mol Med. 2022 Feb;26 (3) :840-854. |[3]Krylova IB, et al., Uridine treatment prevents myocardial injury in rat models of acute ischemia and ischemia/reperfusion by activating the mitochondrial ATP-dependent potassium channel. Sci Rep. 2021 Aug 20;11 (1) :16999.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  Store at room temperature 3 years

• Scientific Category :

  Natural Products

• Clinical Information :

  Launched

• Isoform :

  Human Endogenous Metabolite