mPEG-amine (MW 5000)

mPEG-amine (MW 5000)

• CAS Number: 80506-64-5
• UNSPSC Description: mPEG-amine (mPEG-NH2) (MW 5000) is a modifier that can replace the sulfonic acid portion of the dye molecule to increase the water solubility of long-wavelength voltage-sensitive dyes (VSD) or Pittsburgh (PGH) dyes. mPEG-amine can also form amide bonds with carboxyl groups on the surface of microspheres under the mediation of EDC and Sulfo-NHS to form a PEG coating on the surface of fluorescent microspheres for large-scale rotational cytoplasmic flow studies[1][2].
• Target Antigen: PROTAC Linkers
• Type: Biochemical Assay Reagents
• Related Pathways: PROTAC
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/mpeg-amine-mw-5000.html
• Solubility: 10 mM in DMSO
• Smiles: COCCOCCN.[n]
• Molecular Weight: 5000(Average)
• References & Citations: [1]Patrick MJ, et al. Enhanced aqueous solubility of long wavelength voltage-sensitive dyes by covalent attachment of polyethylene glycol. Org Biomol Chem. 2007 Oct 21;5(20):3347-53.|[2]Suzuki K, et al. Spatial confinement of active microtubule networks induces large-scale rotational cytoplasmic flow. Proc Natl Acad Sci U S A. 2017 Mar 14;114(11):2922-2927.
• Shipping Conditions: Room Temperature
• Clinical Information: No Development Reported