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MPEG-amine (MW 5000)

CAT: 0804-HY-140677-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-140677-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
MPEG-amine (mPEG-NH2) (MW 5000) is a modifier that can replace the sulfonic acid portion of the dye molecule to increase the water solubility of long-wavelength voltage-sensitive dyes (VSD) or Pittsburgh (PGH) dyes. mPEG-amine can also form amide bonds with carboxyl groups on the surface of microspheres under the mediation of EDC and Sulfo-NHS to form a PEG coating on the surface of fluorescent microspheres for large-scale rotational cytoplasmic flow studies[1][2].
CAS Number
80506-64-5
Product Name Alternative
MPEG-NH2 (MW 5000)
UNSPSC
12352200
Hazard Statement
H317, H319
Target
PROTAC Linkers
Type
Biochemical Assay Reagents
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mpeg-amine-mw-5000.html
Purity
99.70
Solubility
10 mM in DMSO
Smiles
COCCOCCN.[n]
Molecular Formula
(C2H4O) nC3H9NO
Molecular Weight
5000 (Average)
Precautions
H317, H319
References & Citations
[1]Patrick MJ, et al. Enhanced aqueous solubility of long wavelength voltage-sensitive dyes by covalent attachment of polyethylene glycol. Org Biomol Chem. 2007 Oct 21;5 (20) :3347-53.|[2]Suzuki K, et al. Spatial confinement of active microtubule networks induces large-scale rotational cytoplasmic flow. Proc Natl Acad Sci U S A. 2017 Mar 14;114 (11) :2922-2927.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Biochemical Assay Reagents
Clinical Information
No Development Reported
Isoform
PEG Linkers