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TAK1-IN-2

CAT: 0804-HY-132172-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-132172-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
TAK1-IN-2 is a potent and selective TAK1 inhibitor, with an IC50> of 2 nM[1].
CAS Number
2763213-98-3
UNSPSC
12352005
Target
MAP3K
Type
Reference compound
Related Pathways
MAPK/ERK Pathway
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/tak1-in-2.html
Purity
98.75
Solubility
DMSO : 10 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(C1=CC2=C(CN(C(C3=NC(C(N(CC4=CC=CC=C4OC(F)F)[C@H](C)C(NC)=O)=O)=CN3)=O)C2)C=C1)N
Molecular Formula
C26H26F2N6O5
Molecular Weight
540.52
References & Citations
[1]Veerman JJN, et, al. Discovery of 2,4-1 H-Imidazole Carboxamides as Potent and Selective TAK1 Inhibitors. ACS Med Chem Lett. 2021 Mar 3;12 (4) :555-562.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
MAP3K7/TAK1

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