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SID 3712249

CAT: 0804-HY-19731-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-19731-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SID 3712249 (MiR-544 Inhibitor 1) is a miR-544 biogenesis inhibitor. SID 3712249 binds directly to the precursor miRNA. SID 3712249 blocks production of the mature microRNA and decreases miR-544, HIF-1α, and ATM transcripts. SID 3712249 can be used in the research of cancers, such as breast cancer[1].
CAS Number
522606-67-3
Product Name Alternative
MiR-544 Inhibitor 1
UNSPSC
12352005
Hazard Statement
H302
Target
Apoptosis; MicroRNA
Type
Reference compound
Related Pathways
Apoptosis; Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/SID-3712249.html
Purity
99.26
Solubility
DMSO : 16.67 mg/mL (ultrasonic)
Smiles
NC1=C2C(C=C(N3CCCC3)N=C2N)=C(C#N)C(N4CCCC4)=N1
Molecular Formula
C17H21N7
Molecular Weight
323.40
Precautions
H302
References & Citations
[1]Christopher L Haga, et al. Small Molecule Inhibition of miR-544 Biogenesis Disrupts Adaptive Responses to Hypoxia by Modulating ATM-mTOR Signaling. ACS Chem Biol. 2015 Oct 16;10 (10) :2267-76.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported