Tos-PEG3

• Description :

  Tos-PEG3 is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Tos-PEG3 (structure 1) can be used for the synthesis of 3'-aminooxy oligonucleotides solid supports[1].

• UNSPSC :

  12352005

• Hazard Statement :

  H302, H315, H319, H335

• Target :

  PROTAC Linkers

• Type :

  Reference compound

• Related Pathways :

  PROTAC

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/tos-peg3.html

• Purity :

  98.0

• Solubility :

  DMSO : 100 mg/mL (ultrasonic;warming)|Ethanol : 100 mg/mL (ultrasonic)|H2O : 10 mg/mL (ultrasonic)

• Smiles :

  OCCOCCOCCOS(C1=CC=C(C)C=C1)(=O)=O

• Molecular Formula :

  C13H20O6S

• Molecular Weight :

  304.36

• Precautions :

  H302, H315, H319, H335

• References & Citations :

  [1]Noël M, et al. Solid Supports for the Synthesis of 3'-Aminooxy Deoxy- or Ribo-oligonucleotides and Their 3'-Conjugation by Oxime Ligation.J Org Chem. 2019 Nov 15;84 (22) :14854-14860.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [77544-68-4]