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SK609

CAT: 0804-HY-W116433Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-W116433Size:1 Each
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Description
SK609 is a selective dopamine D3 receptor agonist with activity that improves dopamine and norepinephrine levels in the cerebral cortex. SK609 has been successfully used to suppress dyskinesias in Parkinson's disease models and alleviated muscle twitches induced by L-dopa. SK609 improved performance in sustained attention tasks by significantly reducing misses and false alarms. SK609 may provide an inhibitory option for suppressing movement and cognitive impairment in patients with Parkinson's disease[1].
CAS Number
144887-95-6
UNSPSC
12352005
Hazard Statement
H315-H319-H320
Target
Dopamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/sk609.html
Smiles
ClC1=C(CCC(C)N)C=CC=C1
Molecular Formula
C10H14ClN
Molecular Weight
183.68
Precautions
P264-P280-P302+P352-P305+P351+P338-P362
References & Citations
[1]A novel dopamine D3R agonist SK609 with norepinephrine transporter inhibition promotes improvement in cognitive task performance in rodent and non-human primate models of Parkinson's disease
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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