Atosiban (acetate)

• UNSPSC Description:

  Atosiban acetate (RW22164 acetate;RWJ22164 acetate) is a nonapeptide competitive vasopressin/oxytocin receptor antagonist, and is a desamino-oxytocin analogue. Atosiban is the main tocolytic agent and has the potential for spontaneous preterm labor research[1].

• Target Antigen:

  Oxytocin Receptor; Vasopressin Receptor

• Type:

  Peptides

• Related Pathways:

  GPCR/G Protein

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer; Endocrinology; Cardiovascular Disease

• Assay Protocol:

  https://www.medchemexpress.com/atosiban-acetate.html

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)|H2O : 50 mg/mL (ultrasonic)

• Smiles:

  O=C([C@H](CSSCCC(N[C@@H](C1=O)CC2=CC=C(OCC)C=C2)=O)NC([C@@H](NC(C(NC([C@](N1)([H])[C@@H](C)CC)=O)[C@H](O)C)=O)CC(N)=O)=O)N(CCC3)[C@@H]3C(N[C@@H](CCCN)C(NCC(N)=O)=O)=O.OC(C)=O

• Molecular Weight:

  1054.24

• References & Citations:

  [1]Sanu O, et al. Critical appraisal and clinical utility of atosiban in the management of preterm labor. Ther Clin Risk Manag. 2010 Apr 26;6:191-9.|[2]Philip J Ryan, et al. Oxytocin-receptor-expressing Neurons in the Parabrachial Nucleus Regulate Fluid Intake. Nat Neurosci. 2017 Dec;20(12):1722-1733.J Pharm Biomed Anal. 11 December 2021, 114518.|Transl Psychiatry. 2024 May 25;14(1):208.|Front Neurosci. 2021 Sep 10;15:723064.|J Pharm Biomed Anal. 2022: 115156.

• Shipping Conditions:

  Blue Ice

• Clinical Information:

  Launched

• CAS Number:

  914453-95-5