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Atosiban

CAT: 0804-HY-17572-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-17572-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Atosiban (RW22164; RWJ22164) is a nonapeptide competitive vasopressin/oxytocin receptor antagonist, and is a desamino-oxytocin analogue. Atosiban is the main tocolytic agent and has the potential for spontaneous preterm labor research[1].
CAS Number
90779-69-4
Product Name Alternative
RW22164; RWJ22164
UNSPSC
12352209
Hazard Statement
H360
Target
Oxytocin Receptor; Vasopressin Receptor
Type
Peptides
Related Pathways
GPCR/G Protein
Applications
Cancer-programmed cell death
Field of Research
Endocrinology; Cancer; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/Atosiban.html
Purity
99.09
Solubility
DMSO : ≥ 16.67 mg/mL|H2O : 16.67 mg/mL (ultrasonic)
Smiles
O=C([C@H](CSSCCC(N[C@@H](C1=O)CC2=CC=C(OCC)C=C2)=O)NC([C@@H](NC(C(NC([C@](N1)([H])[C@@H](C)CC)=O)[C@H](O)C)=O)CC(N)=O)=O)N(CCC3)[C@@H]3C(N[C@@H](CCCN)C(NCC(N)=O)=O)=O
Molecular Formula
C43H67N11O12S2
Molecular Weight
994.19
Precautions
H360
References & Citations
[1]Sanu O, et al. Critical appraisal and clinical utility of atosiban in the management of preterm labor. Ther Clin Risk Manag. 2010 Apr 26;6:191-9.|[2]Philip J Ryan, et al. Oxytocin-receptor-expressing Neurons in the Parabrachial Nucleus Regulate Fluid Intake. Nat Neurosci. 2017 Dec;20 (12) :1722-1733.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
Launched
Citation 01
Curr Biol. 2025 Sep 26:S0960-9822 (25) 01182-0.|Front Neurosci. 2021 Sep 10:15:723064.|J Pharm Biomed Anal. 2023 Feb 5:224:115156.|Neurosci Bull. 2025 Aug 6.|J Pharm Biomed Anal. 2022 Mar 20:211:114518.|Transl Psychiatry. 2024 May 25;14 (1) :208.