Prochloraz (Standard)

• UNSPSC Description:

  Prochloraz (Standard) is the analytical standard of Prochloraz. This product is intended for research and analytical applications. Prochloraz is an imidazole antifungal. Prochloraz is as an estrogen receptor (ER) and androgen receptor (AR) antagonist and an aromatase inhibitor with IC50 values of 25 μM, 4 μM and 0.3 μM, respectively. Prochloraz is able to activate the aryl hydrocarbon receptor (AhR) having an EC50 of 1 μM[1][2].

• Target Antigen:

  Androgen Receptor; Aryl Hydrocarbon Receptor; Estrogen Receptor/ERR; Fungal

• Type:

  Reference Standards

• Related Pathways:

  Anti-infection;Immunology/Inflammation;Vitamin D Related/Nuclear Receptor

• Field of Research:

  Infection; Endocrinology

• Assay Protocol:

  https://www.medchemexpress.com/prochloraz-standard.html

• Smiles:

  O=C(N1C=CN=C1)N(CCC)CCOC2=C(Cl)C=C(Cl)C=C2Cl

• Molecular Weight:

  376.67

• References & Citations:

  [1]E Antignac, et al. Prochloraz as potent inhibitor of benzo[a]pyrene metabolism and mutagenic activity in rat liver fractions. Toxicol Lett. 1990 Dec;54(2-3):309-15.|[2]Anne Marie Vinggaard, et al. Prochloraz: an imidazole fungicide with multiple mechanisms of action. Int J Androl. 2006 Feb;29(1):186-92.

• Shipping Conditions:

  Room temperature

• CAS Number:

  67747-09-5