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Isavuconazonium (sulfate)

CAT: 0804-HY-100373-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-100373-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Isavuconazonium sulfate (BAL8557-002) is an orally active broad-spectrum antifungal molecule. Isavuconazonium sulfate is a precursor of the triazole antifungal active molecule Isavuconazole. Isavuconazonium sulfate can be used in the study of invasive aspergillosis, mucormycosis, blastomycosis, and Acanthamoeba keratitis[1][2][3][4][5].
CAS Number
946075-13-4
Product Name Alternative
BAL8557-002
UNSPSC
12352005
Hazard Statement
H302, H361, H372, H410
Target
Fungal
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/isavuconazonium-sulfate.html
Concentration
10mM
Purity
97.14
Solubility
DMSO : 175 mg/mL (ultrasonic) |H2O : 0.5 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O[C@@](CN(N=C1)C=[N+]1C(C)OC(N(C(N=CC=C2)=C2COC(CNC)=O)C)=O)(C(C=C3F)=C(C=C3)F)[C@H](C4=NC(C(C=C5)=CC=C5C#N)=CS4)C.O=[S]([O-])(O)=O
Molecular Formula
C35H36F2N8O9S2
Molecular Weight
814.84
Precautions
H302, H361, H372, H410
References & Citations
[1]Kovanda L L, et al. Isavuconazonium sulfate: a new agent for the treatment of invasive aspergillosis and invasive mucormycosis[J]. Expert review of clinical pharmacology, 2016, 9 (7) : 887-897.|[2]Shing B, et al. Evaluation of Amebicidal and Cysticidal Activities of Antifungal Drug Isavuconazonium Sulfate against Acanthamoeba T4 Strains. Pharmaceuticals (Basel) . 2021 Dec 11;14 (12) :1294.|[3]Slain D, et al. Isavuconazonium sulfate: a novel antifungal agent[J]. Current Fungal Infection Reports, 2015, 9: 302-313.|[4]Luo G, et al. Isavuconazole therapy protects immunosuppressed mice from mucormycosis[J]. Antimicrobial agents and chemotherapy, 2014, 58 (4) : 2450-2453.|[5]Scolarici MJ, et al. The Role of Isavuconazonium Sulphate for the Treatment of Blastomycosis: A Case Series and Antifungal Susceptibility. Open Forum Infect Dis. 2022 Apr 27;9 (7) :ofac220.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched

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Alternative Products

CatalogName
T3934-01Isavuconazonium sulfate
TRC-I893431-100MGIsavuconazonium Sulfate d3
TRC-C964260-75MG(2S,3S)-Isavuconazonium Sulfate
TRC-N137473-5MGN-Nitroso Isavuconazonium Sulfate
A24588-50Isavuconazonium sulfate (BAL8557-002) 50mg
A24588-10Isavuconazonium sulfate (BAL8557-002) 10mg
A24588-100Isavuconazonium sulfate (BAL8557-002) 100mg
A24588-5Isavuconazonium sulfate (BAL8557-002) 5mg
CS-O-46614Isavuconazonium chloride D5
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