Thalidomide-O-C5-piperidine-NH-Boc

Thalidomide-O-C5-piperidine-NH-Boc

• UNSPSC Description: Thalidomide-O-C5-piperidine-NH-Boc is an E3 Ligase Ligand-Linker Conjugate. Thalidomide-O-C5-piperidine-NH-Boc can be used to synthesize PROTAC PIN1 degrader-1 (HY-168037)[1].
• Target Antigen: E3 Ligase Ligand-Linker Conjugates
• Type: Reference compound
• Related Pathways: PROTAC
• Applications: Cancer-programmed cell death
• Field of Research: cancer
• Assay Protocol: https://www.medchemexpress.com/thalidomide-o-c5-piperidine-nh-boc.html
• Smiles: O=C1C2=C(C(OCCCCCN3CCC(NC(OC(C)(C)C)=O)CC3)=CC=C2)C(N1C(C(N4)=O)CCC4=O)=O
• Molecular Weight: 542.62
• References & Citations: [1]Liu C, et al. Re-Evaluating PIN1 as a Therapeutic Target in Oncology Using Neutral Inhibitors and PROTACs. J Med Chem. 2024 Sep 12;67(17):15780-15795.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported