Thalidomide-NH-C5-azacyclohexane-N-Boc

Thalidomide-NH-C5-azacyclohexane-N-Boc

• CAS Number: 2710222-09-4
• UNSPSC Description: Thalidomide-NH-C5-azacyclohexane-N-Boc is an E3 Ligase Ligand-Linker Conjugate. Thalidomide-NH-C5-azacyclohexane-N-Boc can be used to synthesize XD2-149 (HY-159570)[1].
• Target Antigen: E3 Ligase Ligand-Linker Conjugates
• Type: Reference compound
• Related Pathways: PROTAC
• Applications: Cancer-programmed cell death
• Field of Research: cancer
• Assay Protocol: https://www.medchemexpress.com/thalidomide-nh-c5-azacyclohexane-n-boc.html
• Smiles: O=C(NCCN1CCC(CCCCCNC2=CC=CC(C(N3C4C(NC(CC4)=O)=O)=O)=C2C3=O)CC1)OC(C)(C)C
• Molecular Weight: 569.69
• References & Citations: [1]Hanafi M, et al. Discovery of a Napabucasin PROTAC as an Effective Degrader of the E3 Ligase ZFP91. J Med Chem. 2021 Feb 11;64(3):1626-1648.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported