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Verticilide

CAT: 0804-HY-N7491Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-N7491Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Verticilide is a ryanodine-binding inhibitor and inhibits ryanodine binding to ryanodine receptors in the cockroach at an IC50 value of 4.2 μM (whereas inhibition against mouse ryanodine receptors was weak (IC50=53.9 μM) ) [1].
CAS Number
693778-57-3
UNSPSC
12352209
Target
Calcium Channel
Type
Natural Products
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/verticilide.html
Solubility
10 mM in DMSO
Smiles
CCCCC[C@@H](OC([C@@H](N(C([C@H](OC([C@@H](N(C1=O)C)C)=O)CCCCC)=O)C)C)=O)C(N([C@H](C(O[C@@H](C(N([C@H](C(O[C@@H]1CCCCC)=O)C)C)=O)CCCCC)=O)C)C)=O
Molecular Formula
C44H76N4O12
Molecular Weight
853.09
References & Citations
[1]Kazuro Shiomi, et al. Verticilide, a new ryanodine-binding inhibitor, produced by Verticillium sp. FKI-1033. J Antibiot (Tokyo) . 2010 Feb;63 (2) :77-82.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported

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