Ent- (+) -Verticilide

CAT: 0931-T86371-01Size: 10 mgDry Ice: NoHazardous: No

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CAT#:0931-T86371-01Size:10 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

2056011-05-1

Target

Calcium Channel

Related Pathways

Metabolism, Membrane transporter/Ion channel

Bioactivity

Ent- (+) -verticilide is an effective and specific inhibitor of cardiac ryanodine receptor (RyR2) calcium release channels, demonstrating antiarrhythmic properties. It suppresses RyR2-mediated diastolic Ca2+ leak and shows greater potency and a unique action mechanism compared to Dantrolene and Tetracaine. ent- (+) -verticilide serves as a valuable tool for exploring the therapeutic potential of addressing RyR2 hyperactivity in cardiac and neurological conditions [1].

Smiles

C(CCCC)[C@H]1C(=O)N(C)[C@H](C)C(=O)O[C@@H](CCCCC)C(=O)N(C)[C@H](C)C(=O)O[C@@H](CCCCC)C(=O)N(C)[C@H](C)C(=O)O[C@@H](CCCCC)C(=O)N(C)[C@H](C)C(=O)O1

Molecular Formula

C44H76N4O12

Molecular Weight

853.09

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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GTR19235399-01	Ent- (+) -Verticilide
HY-N7491	Verticilide
BA8583-5	ENT-C225
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FE22696-01	Ent-tadalafil
GGA13044-01	Ent-alvimopan
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N379365	ent-Nateglinide
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Ent- (+) -Verticilide

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