Vismodegib (Standard)

CAT: 0804-HY-10440R-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-10440R-01Size:5 mg
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Description
Vismodegib (Standard) is the analytical standard of Vismodegib. This product is intended for research and analytical applications. Vismodegib (GDC-0449) is an orally active hedgehog pathway inhibitor with an IC50 of 3 nM. Vismodegib also inhibits P-gp, ABCG2 with IC50 values of 3.0 μM and 1.4 μM, respectively[1][2].
CAS Number
[879085-55-9]
Product Name Alternative
GDC-0449 (Standard)
UNSPSC
12352005
Target
Autophagy; Hedgehog; Reference Standards
Type
Reference Standards
Related Pathways
Autophagy; Others; Stem Cell/Wnt
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/vismodegib-standard.html
Smiles
O=C(C1=CC=C(C=C1Cl)S(=O)(C)=O)NC2=CC=C(C(C3=NC=CC=C3)=C2)Cl
Molecular Formula
C19H14Cl2N2O3S
Molecular Weight
421.30
References & Citations
2+
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

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