Recombinant Human CCL14 Protein

Recombinant Human CCL14 Protein

• Background: Has weak activities on human monocytes and acts via receptors that also recognize MIP-1 alpha. It induces intracellular Ca2+ changes and enzyme release, but no chemotaxis, at concentrations of 100-1,000 nM, and is inactive on T-lymphocytes, neutrophils, and eosinophil leukocytes. Enhances the proliferation of CD34 myeloid progenitor cells. The processed form HCC-1(9-74) is a chemotactic factor that attracts monocytes, eosinophils, and T-cells and is a ligand for CCR1, CCR3 and CCR5.
• Abbreviation: CCL14
• Synonyms: C-C motif chemokine 14, CC-1, CC-3, HCC-1, HCC-1(1-74), HCC-3, NCC-2, NCC2, SCYA14, Small-inducible cytokine A14
• UniProt: Q16627
• Accession Number: Q16627
• Host: E. coli
• Origin Species: Human
• Tag: N-His
• Sequence: Thr20-Asn93
• Field of Research: Immunology;Cardiovascular
• Purity: > 95% as determined by reducing SDS-PAGE.
• Bioactivity: Not validated for activity
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
• Molecular Weight: 12 kDa
• Shipping Conditions: This product is provided as lyophilized powder which is shipped with ice packs.
• Storage Conditions: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.