Thalidomide- (2) piperidine

• Description :

  Thalidomide- (2) piperidine (compound 9) is a potent E3 ligase ligand. Thalidomide- (2) piperidine can be used for synthesis of PROTACs[1].

• UNSPSC :

  12352005

• Hazard Statement :

  H302-H315-H319-H335

• Target :

  Ligands for E3 Ligase

• Type :

  Reference compound

• Related Pathways :

  PROTAC

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/androgen-receptor-degrader-2.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(C1=C2C=C3CNCCC3=C1)N(C(CC4)C(NC4=O)=O)C2=O.Cl

• Molecular Formula :

  C16H16ClN3O4

• Molecular Weight :

  349.77

• Precautions :

  P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

• References & Citations :

  [1]Shao MW, et, al. Androgen receptor protein degraders with a tricyclic cereblon ligand. WO2021231927A1.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  Cereblon

• CAS Number :

  [2616553-33-2]