Methyl 3,4-dihydroxybenzoate-d3-1

Methyl 3,4-dihydroxybenzoate-d3-1

• CAS Number: 2733147-54-9
• UNSPSC Description: Methyl 3,4-dihydroxybenzoate-d3-1 is the deuterium labeled Methyl 3,4-dihydroxybenzoate. Methyl 3,4-dihydroxybenzoate (Protocatechuic acid methyl ester; Methyl protocatechuate) is a major metabolite of antioxidant polyphenols found in green tea. Antioxidant and anti-inflammatory effect[1].
• Target Antigen: Apoptosis; Isotope-Labeled Compounds; Keap1-Nrf2
• Type: Isotope-Labeled Compounds
• Related Pathways: Apoptosis;NF-κB;Others
• Field of Research: Cancer; Inflammation/Immunology
• Solubility: 10 mM in DMSO
• Smiles: O=C(OC)C1=C([2H])C([2H])=C(O)C(O)=C1[2H]
• Molecular Weight: 171.17
• References & Citations: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. |[2]Ameeramja J, et al. Protocatechuic acid methyl ester ameliorates fluoride toxicity in A549 cells. Food Chem Toxicol. 2017 Nov;109(Pt 2):941-950.|[3]Ameeramja J, et al. Protocatechuic acid methyl ester modulates fluoride induced pulmonary toxicity in rats. Food Chem Toxicol. 2018 Aug;118:235-244.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported