NT1-O12B
CAT:
804-HY-137499-04
Size:
25 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
NT1-O12B
- CAS Number: 2739805-63-9
- UNSPSC Description: NT1-O12B, an endogenous chemical and a neurotransmitter-derived lipidoid (NT-lipidoid), is an effective carrier for enhanced brain delivery of several blood-brain barrier (BBB)-impermeable cargos. Doping NT1-O12B into BBB-impermeable lipid nanoparticles (LNPs) gives the LNPs the ability to cross the BBB. NT-lipidoids formulation not only facilitate cargo crossing of the BBB, but also delivery of the cargo into neuronal cells for functional gene silencing or gene recombination[1].
- Target Antigen: Endogenous Metabolite; Liposome
- Type: Oligonucleotides
- Related Pathways: Metabolic Enzyme/Protease
- Field of Research: Neurological Disease
- Assay Protocol: https://www.medchemexpress.com/nt1-o12b.html
- Smiles: CCCCCCCCSSCCOC(CCN(CCC(OCCSSCCCCCCCC)=O)CCC1=CNC2=C1C=CC=C2)=O
- Molecular Weight: 713.13
- References & Citations: [1]Ma F, et al. Neurotransmitter-derived lipidoids (NT-lipidoids) for enhanced brain delivery through intravenous injection. Sci Adv. 2020;6(30):eabb4429. Published 2020 Jul 24.
- Shipping Conditions: Room Temperature