Pomalidomide-C12-NH2 (hydrochloride)
CAT:
804-HY-145615-02
Size:
10 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Pomalidomide-C12-NH2 (hydrochloride)
- CAS Number: 2862774-02-3
- UNSPSC Description: Pomalidomide-C12-NH2 hydrochloride is the E3 ligase ligand-linker conjugate of PROTAC KRAS G12C degrader-1 (HY-139186). PROTAC KRAS G12C degrader-1 is a Cereblon-based KRASG12C degrader[1].
- Target Antigen: E3 Ligase Ligand-Linker Conjugates
- Type: Reference compound
- Related Pathways: PROTAC
- Applications: Cancer-programmed cell death
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/pomalidomide-c12-nh2-hydrochloride.html
- Solubility: 10 mM in DMSO
- Smiles: NCCCCCCCCCCCCNC1=C(C(N(C2CCC(NC2=O)=O)C3=O)=O)C3=CC=C1.Cl
- Molecular Weight: 493.04
- References & Citations: [1]Zeng M, et, al. Exploring Targeted Degradation Strategy for Oncogenic KRAS G12C. Cell Chem Biol. 2020 Jan 16;27(1):19-31.e6.
- Shipping Conditions: Blue Ice
- Clinical Information: No Development Reported