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PROTAC BCR-ABL Degrader-1

CAT:
804-HY-153415-02
Size:
5 mg
Price:
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For price, please contact [email protected]
  • Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
  • Dry Ice Shipment: No
PROTAC BCR-ABL Degrader-1 - image 1

PROTAC BCR-ABL Degrader-1

  • UNSPSC Description: PROTAC BCR-ABL Degrader-1 (compound PROTAC 1) is a PROTAC with a 2-oxoethyl linker. PROTAC BCR-ABL Degrader-1 induces Bcr-Abl degradation in a ubiquitinproteasom-dependent manner. PROTAC BCR-ABL Degrader-1 exhibits antiproliferative activity against K562 cells, and has the potential to study cancer[1].
  • Target Antigen: Bcr-Abl; PROTACs
  • Type: Reference compound
  • Related Pathways: PROTAC;Protein Tyrosine Kinase/RTK
  • Applications: Cancer-Kinase/protease
  • Field of Research: Cancer
  • Assay Protocol: https://www.medchemexpress.com/protac-bcr-abl-degrader-1.html
  • Solubility: DMSO : 100 mg/mL (ultrasonic)
  • Smiles: CC(C=CC(NC(C1=CC=C(CN2CCN(CC(NC3=CC=CC4=C3C(N(C5C(NC(CC5)=O)=O)C4=O)=O)=O)CC2)C=C1)=O)=C6)=C6NC7=NC=CC(C8=CC=CN=C8)=N7
  • Molecular Weight: 792.84
  • References & Citations: [1]Li C, et al. Proteolysis Targeting Chimeras (PROTACs) Based on Imatinib Induced Degradation of BCR-ABL in K562 Cells. ChemistrySelect, 2023, 8(15): e202300095.
  • Shipping Conditions: Room Temperature
  • Clinical Information: No Development Reported