Tec-IN-6

• UNSPSC Description:

  Tec-IN-6 (compound 6) is a FGF2 binding to Tec kinase inhibitor, with an IC50 of 8.9 μM (His-FGF2/GST-NΔ173 Tec)[1].

• Target Antigen:

  FGFR; Tyrosinase

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease;Protein Tyrosine Kinase/RTK

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/tec-in-6.html

• Smiles:

  O=C(OCC(N=C1N2C(C)=CC=C1)=CC2=O)C3=C(C(C(OC)=O)=C(N3)C)C

• Molecular Weight:

  369.37

• References & Citations:

  [1]Giuseppe La Venuta, et al. Small Molecule Inhibitors Targeting Tec Kinase Block Unconventional Secretion of Fibroblast Growth Factor 2. J Biol Chem. 2016 Aug 19;291(34):17787-803.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  923762-87-2