2-Hydroxybutyric acid (Standard)

• UNSPSC Description:

  2-Hydroxybutyric acid (Standard) is the analytical standard of 2-Hydroxybutyric acid. This product is intended for research and analytical applications. 2-Hydroxybutyric acid (α-Hydroxybutyric acid ) is converted from 2-Aminobutyric acid, with 2-oxobutyric acid as an intermediate metabolite[1]. 2-Hydroxybutyric acid is a potential biomarker for type 2 diabetes and preeclampsia[2][4]. 2-Hydroxybutyric acid prevents the acetaminophen (AP)-induced liver injury[3].

• Target Antigen:

  Endogenous Metabolite

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Field of Research:

  Metabolic Disease; Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/2-hydroxybutyric-acid-standard.html

• Smiles:

  CCC(O)C(O)=O

• Molecular Weight:

  104.10

• References & Citations:

  [1]Landaas S, et al. The formation of 2-hydroxybutyric acid in experimental animals. Clin Chim Acta. 1975 Jan 6;58(1):23-32.|[2]Shantavasinkul PC, et al., Improvement in insulin resistance after gastric bypass surgery is correlated with a decline in plasma 2-hydroxybutyric acid. Surg Obes Relat Dis. 2018 Aug;14(8):1126-1132.|[3]Zheng N, et al., Vancomycin pretreatment attenuates acetaminophen-induced liver injury through 2-hydroxybutyric acid. J Pharm Anal. 2020 Dec;10(6):560-570.|[4]Wang F, et al., Metabolomic analysis-identified 2-hydroxybutyric acid might be a key metabolite of severe preeclampsia. Open Life Sci. 2023 Feb 28;18(1):20220572.

• Shipping Conditions:

  Room temperature

• CAS Number:

  600-15-7