7,3',4'-Trihydroxyisoflavone

CAT:

804-HY-124953-01

Size:

10 mg

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CAS Number: 485-63-2
UNSPSC Description: 7,3',4'-Trihydroxyisoflavone, a major metabolite of Daidzein, is an ATP-competitive inhibitor of Cot (Tpl2/MAP3K8) and MKK4. 7,3',4'-Trihydroxyisoflavone has anticancer, anti-angiogenic, chemoprotective, and free radical scavenging activities[1][2].
Target Antigen: Apoptosis; MAP3K
Type: Reference compound
Related Pathways: Apoptosis;MAPK/ERK Pathway
Field of Research: Cancer
Assay Protocol: https://www.medchemexpress.com/7-3-4-trihydroxyisoflavone.html
Purity: 99.98
Solubility: DMSO : 100 mg/mL (ultrasonic)
Smiles: OC1=CC=C2C(C(C3=CC(O)=C(C=C3)O)=COC2=C1)=O
Molecular Weight: 270.24
References & Citations: [1]Yu-Li Lo, et al. 7,3',4'-Trihydroxyisoflavone modulates multidrug resistance transporters and induces apoptosis via production of reactive oxygen species. Toxicology. 2012 Dec 16;302(2-3):221-32. |[2]Dong Eun Lee, et al. 7,3',4'-Trihydroxyisoflavone, a metabolite of the soy isoflavone daidzein, suppresses ultraviolet B-induced skin cancer by targeting Cot and MKK4. J Biol Chem. 2011 Apr 22;286(16):14246-56.
Shipping Conditions: Blue Ice
Storage Conditions: -20°C, 3 years (Powder)
Clinical Information: No Development Reported

Cat	Name
1886-100	7,3',4'-Trihydroxyisoflavone
1886-25	7,3',4'-Trihydroxyisoflavone
MBS6071934-02	7,3',4'-Trihydroxyisoflavone (3-(3,4-Dihydroxyphenyl)-7-hydroxy-4H-chromen-4-one, 3'-Hydroxydiadzein, THIF, 7,3',4'-THIF)
MBS6071934-01	7,3',4'-Trihydroxyisoflavone (3-(3,4-Dihydroxyphenyl)-7-hydroxy-4H-chromen-4-one, 3'-Hydroxydiadzein, THIF, 7,3',4'-THIF)
MBS6071934-03	7,3',4'-Trihydroxyisoflavone (3-(3,4-Dihydroxyphenyl)-7-hydroxy-4H-chromen-4-one, 3'-Hydroxydiadzein, THIF, 7,3',4'-THIF)
TRC-T795360-50MG	4',6,7-Trihydroxyisoflavone
TRC-T795360-100MG	4',6,7-Trihydroxyisoflavone
TRC-T795360-5MG	4',6,7-Trihydroxyisoflavone
MBS5761701-01	7,3',4'-Trihydroxyflavone
TBW00581	7,3',4'-Trihydroxyflavone