7,3',4'-Tri-O-methylluteolin
CAT:
804-HY-N7012-02
Size:
10 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
7,3',4'-Tri-O-methylluteolin
- CAS Number: 29080-58-8
- UNSPSC Description: 7,3',4'-Tri-O-methylluteolin (5-Hydroxy-3',4',7-trimethoxyflavone), a flavonoid compound, possesses potent anti-inflammatory effects in LPS-induced macrophage cell line mediated by inhibition of release of inflammatory mediators, NO, PGE2, and pro-inflammatory cytokines. 7,3',4'-Tri-O-methylluteolin significantly induces reduction in the mRNA expressions of inducible nitric oxide synthase and cyclooxygenase-2[1].
- Target Antigen: COX; Interleukin Related; TNF Receptor
- Type: Natural Products
- Related Pathways: Apoptosis;Immunology/Inflammation
- Applications: Metabolism-protein/nucleotide metabolism
- Field of Research: Inflammation/Immunology
- Assay Protocol: https://www.medchemexpress.com/7-3-4-tri-o-methylluteolin.html
- Purity: 99.28
- Solubility: DMSO : 20 mg/mL (ultrasonic)
- Smiles: OC1=C2C(OC(C3=CC=C(OC)C(OC)=C3)=CC2=O)=CC(OC)=C1
- Molecular Weight: 328.32
- References & Citations: [1]Sudha, A, et al. Protective effect of 5-hydroxy-3′,4′,7-trimethoxyflavone against inflammation induced by lipopolysaccharide in RAW 264.7 macrophage: in vitro study and in silico validation. Medicinal Chemistry Research, 2016,25(9), 1754–1767.
- Shipping Conditions: Room Temperature
- Storage Conditions: 4°C (Powder, protect from light)
- Clinical Information: No Development Reported