Thalidomide-O-amido-PEG4-C2-NH2 (hydrochloride)
CAT:
804-HY-122710A-05
Size:
100 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Thalidomide-O-amido-PEG4-C2-NH2 (hydrochloride)
- CAS Number: 2245697-85-0
- UNSPSC Description: Thalidomide-O-amido-PEG4-C2-NH2 hydrochloride, a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker, can be used in the synthesis of PROTACs[1].
- Target Antigen: Apoptosis; Autophagy; E3 Ligase Ligand-Linker Conjugates
- Type: Reference compound
- Related Pathways: Apoptosis;Autophagy;PROTAC
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/thalidomide-o-amido-peg4-c2-nh2-hydrochloride.html
- Purity: 95.0
- Solubility: DMSO : 50 mg/mL (ultrasonic)
- Smiles: O=C(NCCOCCOCCOCCOCCN)COC1=CC=CC(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O.[H]Cl
- Molecular Weight: 587.02
- References & Citations: [1]James Bradner, et al. Methods to induce targeted protein degradation through bifunctional molecules. WO2016105518A1.
- Shipping Conditions: Room Temperature
- Storage Conditions: 4°C (Powder, sealed storage, away from moisture)
- Clinical Information: No Development Reported