MEK-5 rabbit pAb
CAT:
855-ES20665-01
Size:
50 μL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
MEK-5 rabbit pAb
- Description: The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically interacts with and activates MAPK7/ERK5. This kinase itself can be phosphorylated and activated by MAP3K3/MEKK3, as well as by atypical protein kinase C isoforms (aPKCs). The signal cascade mediated by this kinase is involved in growth factor stimulated cell proliferation and muscle cell differentiation. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been described. [provided by RefSeq, May 2011],
- Synonyms: MAP2K5; MEK5; MKK5; PRKMK5; Dual specificity mitogen-activated protein kinase kinase 5; MAP kinase kinase 5; MAPKK 5; MAPK/ERK kinase 5; MEK 5
- Gene ID: 5067
- UniProt: Q13163
- Cellular Locus: Nucleus,cytoplasm,spindle,cytosol,
- Host: Rabbit
- Species Reactivity: Human, Mouse, Rat
- Immunogen: Recombinant Protein of MEK-5
- Clonality: Polyclonal
- Validated Applications: WB, IHC, IF
- Stability: 1 year
- Dilution: WB: 1:1000-2000 IHC: 1:200-500
- Molecular Weight: 49kD
- Storage Conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.