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20α-Dihydroprogesterone

CAT: 0804-HY-113062-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-113062-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
20α-Dihydroprogesterone is the metabolite of Progesterone. 20α-Dihydroprogesterone inhibits cell proliferation and migration in breast tissue. 20α-Dihydroprogesterone inhibits aromatase in cell MCF-7aro with IC50 about 5 μM[1].
CAS Number
145-14-2
Product Name Alternative
20-OH-P
UNSPSC
12352211
Hazard Statement
H351, H360
Target
Cytochrome P450; Endogenous Metabolite
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Cancer; Endocrinology
Assay Protocol
https://www.medchemexpress.com/20α-dihydroprogesterone.html
Purity
98.07
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
C[C@@]12[C@]3([H])[C@](CCC1=CC(CC2)=O)([H])[C@@]4([H])[C@](CC3)([C@@](CC4)([H])[C@@H](O)C)C
Molecular Formula
C21H32O2
Molecular Weight
316.48
Precautions
H351, H360
References & Citations
[1]Pasqualini JR, et al., The anti-aromatase effect of progesterone and of its natural metabolites 20alpha- and 5alpha-dihydroprogesterone in the MCF-7aro breast cancer cell line. Anticancer Res. 2008 Jul-Aug;28 (4B) :2129-33.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
Human Endogenous Metabolite

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