Anti-Catenin, gamma (Cardiomyocyte Marker) (11E4)

• Description:

  Gamma catenin, also known as JUP or junction plakoglobin, is a member of the catenin family. The catenins (alpha, beta, gamma, and delta) are ubiquitously expressed, cytoplasmic proteins that associate with E-cadherin at cellular junctions. Catenin/cadherin complexes play an important role in mediating cellular adhesion, including adherens junctions. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

• Synonyms:

  Gamma catenin; JUP, Junction plakoglobin; Catenin gamma

• UNSPSC:

  41116161

• UNSPSC Description:

  Primary and secondary antibodies for multiple methodology immunostaining detection application

• Gene Name:

  JUP

• Gene ID:

  3728

• NCBI Gene ID:

  514174

• UniProt:

  P14923

• Cellular Locus:

  Plasma membrane

• Host:

  Mouse

• Species Reactivity:

  Human, Mouse

• Immunogen:

  fused to maltose binding protein|Recombinant full length human plakoglobin

• Target Antigen:

  Gamma-catenin

• Clonality:

  Monoclonal

• Isotype:

  IgG1 κ

• Clone:

  11E4

• Conjugation:

  Purified, with BSA

• Source:

  Animal

• Applications:

  Flow, intracellular (verified) | IF (verified) | WB (verified)

• Validated Applications:

  FC, IF, WB

• Field of Research:

  Cancer, Cell adhesion, Developmental biology, Signal transduction

• Positive Control:

  A431, T47D or MCF-7 cells. Skin

• Concentration:

  0.2 mg/mL

• Buffer:

  PBS, 0.05% BSA, 0.05% azide

• Molecular Weight:

  80-87 kDa

• Additionnal Information:

  Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody|Immunofluorescence: 1-2 ug/mL|Flow Cytometry 0.5-1 ug/million cells/0.1 mL|Western blotting 0.5-1 ug/mL|Optimal dilution for a specific application should be determined by user

• Shipping Conditions:

  Room temperature

• Storage Conditions:

  4°C; Stable at room temperature or 37°C (98°F) for 7 days.

• Shelf Life:

  2 years

• CAS Number:

  9007-83-4