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MPI-0479605

CAT: 0804-HY-12660-01Size: 2 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-12660-01Size:2 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
MPI-0479605 is a potent and selective ATP-competitive inhibitor of Mps1, with an IC50 of 1.8 nM.
CAS Number
1246529-32-7
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Apoptosis; Mps1
Type
Reference compound
Related Pathways
Apoptosis; Cell Cycle/DNA Damage; Cytoskeleton
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/MPI-0479605.html
Purity
99.54
Solubility
DMSO : 11 mg/mL (ultrasonic; warming)
Smiles
CC(C=C(N1CCOCC1)C=C2)=C2NC3=NC4=C(N=CN4)C(NC5CCCCC5)=N3
Molecular Formula
C22H29N7O
Molecular Weight
407.51
Precautions
H302, H315, H319, H335
References & Citations
[1]Tardif KD, et al. Characterization of the cellular and antitumor effects of MPI-0479605, a small-molecule inhibitor of the mitotic kinase Mps1. Mol Cancer Ther. 2011 Dec;10 (12) :2267-2275.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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