SRD5A1-IN-1

CAT:

804-HY-152094-04

Size:

10 mM / 1 mL

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CAS Number: 2279077-93-7
UNSPSC Description: SRD5A1-IN-1 (Compound 4) is a competitive and covalent steroid 5α-reductase type 1 (SRD5A1) inhibitor with an IC50 of 1.44 µM. SRD5A1-IN-1 modulates SRD5A1 function, leading to a lower level of dihydrotestosterone (DHT) production and SRD5A1 protein suppression[1].
Target Antigen: 5 alpha Reductase; Others
Type: Reference compound
Related Pathways: Metabolic Enzyme/Protease;Others
Applications: Metabolism-protein/nucleotide metabolism
Field of Research: Endocrinology
Assay Protocol: https://www.medchemexpress.com/srd5a1-in-1.html
Solubility: DMSO : 100 mg/mL (ultrasonic)
Smiles: O=C(NC1=CC(C(F)(F)F)=CC(C(F)(F)F)=C1)/C=C/C2=CC(O)=C(C=C2)O
Molecular Weight: 391.26
References & Citations: [1]Lin A C K, et al. Caffeic acid N-[3, 5-bis (trifluoromethyl) phenyl] amide as a non-steroidal inhibitor for steroid 5α-reductase type 1 using a human keratinocyte cell-based assay and molecular dynamics. Scientific Reports, 2022, 12(1): 1-20.
Shipping Conditions: Room Temperature
Clinical Information: No Development Reported

Cat	Name
HY-152094-06	SRD5A1-IN-1
HY-152094-05	SRD5A1-IN-1
HY-152094-02	SRD5A1-IN-1
HY-152094-01	SRD5A1-IN-1
HY-152094-04	SRD5A1-IN-1
HY-152094-03	SRD5A1-IN-1
HY-RS13754	SRD5A1 Human Pre-designed siRNA Set A
HY-163546	HSV-1-IN-1
HY-163731-01	EGR-1-IN-1
HY-159569-04	TfR-1-IN-1