MCP-1/CCL2, Human (Biotinylated, HEK293, His-Avi)
CAT:
804-HY-P78173-01
Size:
50 µg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
MCP-1/CCL2, Human (Biotinylated, HEK293, His-Avi)
- UNSPSC Description: MCP-1/CCL2 Protein, Human (Biotinylated, HEK293, His-Avi) is a cytokine belonging to the CC chemokine family that interacts with the CCR2 chemokine receptor on the cell surface to mediate inflammatory immune responses, viral infections, and tumorigenesis. MCP-1/CCL2 Protein MCP-1/CCL2 Protein, Human (Biotinylated, HEK293, His-Avi) is a biotinylated recombinant human MCP-1/CCL2 (Q24-T99) expressed by HEK293 with His and Avi tags at the C-terminus[1].
- Type: Recombinant Proteins
- Assay Protocol: https://www.medchemexpress.com/cytokines/mcp-1-ccl2-protein-human-biotinylated-hek293-his-avi.html
- Purity: 95.0
- Molecular Weight: 13-20 kDa
- References & Citations: [1]Qiongyu Hao, et al. CCL2/CCR2 signaling in cancer pathogenesis. Cell Commun Signal. 2020 May 29;18(1):82.|[2]Svetlana M Stamatovic, et al. Monocyte chemoattractant protein-1 regulation of blood-brain barrier permeability. J Cereb Blood Flow Metab. 2005 May;25(5):593-606.|[3]Rachel N Gomes, et al. Bacterial clearance in septic mice is modulated by MCP-1/CCL2 and nitric oxide. Shock. 2013 Jan;39(1):63-9.|[4]Seungeun Lee, et al. Tumor-associated macrophages secrete CCL2 and induce the invasive phenotype of human breast epithelial cells through upregulation of ERO1-α and MMP-9. Cancer Lett. 2018 Nov 28;437:25-34.|[5]Robert D Loberg, et al. CCL2 is a potent regulator of prostate cancer cell migration and proliferation. Neoplasia. 2006 Jul;8(7):578-86.
- Shipping Conditions: Blue Ice
- Storage Conditions: Stored at -20°C for 2 years