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HighYield T7 mRNA Uridine Modification Testkit (ARCA)

CAT: 0220-RNT-137Size: 1 KitDry Ice: NoHazardous: No
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CAT#:0220-RNT-137Size:1 Kit
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Description
HighYield T7 mRNA Uridine Modification Testkit is designed to produce large amounts of differentially uridine-modified (m)RNA via in vitro transcription with T7 RNA polymerase. Included Cap analog ARCA allows additional co-transcriptional introduction of a Cap 0 moiety. The resulting 5’-capped (m)RNA can subsequently be used for microinjection, transfection or in vitro translation experiments. Epigenetic internal mRNA modifications e.g. (pseudo)uridine methylation or thiolation as well as 5'-capping have been shown to increase translation efficiency and to reduce immunogenicity [1]-[7] however, the optimal combination needs to be individually termined for each mRNA target.
Product Name Alternative
Synthesis of differentially uridine-modified (m) RNA with Cap 0 structure
Synonyms
Synthesis of differentially uridine-modified (m)RNA with Cap 0 structure
UNSPSC
41100000
UNSPSC Description
Laboratory and scientific equipment
HS Code
38220000
eClass Number
32160405
eClass Product Group
Biochemikalie (Labor, Sonstige)
Autoclavability
—
Shipping Conditions
Shipped on gel packs
Storage Conditions
Avoid freeze/thaw cycles
Storage Temperature
Store at -20 °C
Shelf Life
12 months after date of delivery
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