H-Ras ΔC (S17N) Harvey rat sarcoma viral oncogene homolog, residues 1-166 human, recombinant, E. coli

H-Ras ΔC (S17N) Harvey rat sarcoma viral oncogene homolog, residues 1-166 human, recombinant, E. coli

• Description: Ras proteins are members of the superfamily of small GTP-binding proteins that function as molecular switches controlling a variety of signaling and transport pathways. H-Ras is one of the classic human Ras proteins (H-, N-, K-Ras4A, and K-Ras4B). H-Ras ΔC (aa 1 - 171) lacks the C-terminus with the CaaX recognition sequence necessary for anchoring Ras into the plasma membrane. The mutation S17N results in a 40-fold increase in the affinity for GTP without affecting its affinity for GDP. Protein preparation is 95% GDP- and 5% GTP-loaded, measured by HPLC.
• CAS Number: 9000-83-3
• UNSPSC: 12352202
• UNSPSC Description: Proteins
• HS Code: 35079090
• Accession Number: NP_005334
• eClass Number: 34160400
• eClass Product Group: Peptide and Protein
• Purity: > 90 % (SDS-PAGE)
• Form: Liquid (Supplied in 64 mM Tris-HCl pH 7.2, 10 mM MgCl2 and 5 mM DTE)
• Autoclavability: false
• Shipping Conditions: Shipped on dry ice.
• Storage Conditions: Store at -80 °C. Avoid freeze/thaw cycles.
• Shelf Life: 12 months