Delta-catenin Recombinant Rabbit Monoclonal Antibody [JE75-34]

Delta-catenin Recombinant Rabbit Monoclonal Antibody [JE75-34]

• Description: δ-Catenin is a subfamily of catenin proteins with ten armadillo-repeats and includes the proteins catenin delta-1 and catenin delta-2. Catenin delta-2 is expressed in the brain where it is important for normal cognitive development. Like β-catenin and γ-catenin, δ-catenins seem to interact with presenilins. These catenin-presenilin interaction have implications for cadherin function and regulation of cell-to-cell adhesion. While β-catenin acts as a transcription regulatory protein in the Wnt/TCF pathway, delta-1 catenin has been implicated as a regulator of the NF-κB transcription factor. Palmitoylation of δ-catenin seems to coordinate activity-dependent changes in synaptic adhesion molecules, synapse structure, and receptor localizations that are involved in memory formation.
• Product Name Alternative: ARM-repeat protein antibody Catenin (cadherin associated protein) delta 2 antibody catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein) antibody Catenin delta 2 antibody Catenin delta-2 antibody CTND2_HUMAN antibody CTNND 2 antibody Ctnnd2 antibody Delta catenin antibody Delta-catenin antibody GT 24 antibody GT24 antibody Neural plakophilin related arm repeat protein antibody Neural plakophilin related armadillo repeat protein antibody Neural plakophilin-related ARM-repeat protein antibody Neural plakophilin-related, Neurojungin antibody Neurojungin antibody NPRAP antibody T cell delta catenin antibody
• Abbreviation: CTNND2, NPRAP
• CAS Number: 9000-83-3
• Swiss Prot: Q9UQB3 Human, O35927 Mouse, O35116 Rat
• Cellular Locus: Nucleus, Cell junction, adherens junction, Cell projection, dendrite, Perikaryon.
• Host: Rabbit
• Species Reactivity: Human, Mouse, Rat
• Immunogen: Recombinant protein within Mouse Catenin delta-2 aa 1-100 / 1,247.
• Isotype: IgG
• Clone: JE75-34
• Conjugation: Non-conjugated
• Type: Recombinant Rabbit monoclonal Antibody
• Applications: WB, IHC-P, IP, IHC-Fr
• Positive Control: Mouse brain tissue lysate, mouse hippocampus tissue lysate, mouse cerebellum tissue lysate, rat brain tissue lysate, rat hippocampus tissue lysate, rat cerebellum tissue lysate, human brain tissue, mouse brain tissue, rat brain tissue.
• Concentration: 1 mg/mL
• Dilution: WB: 1:1,000 ;IHC-P: 1:200 ;IP: 1-2μg/sample ;IHC-Fr: 1:200
• Purity: Protein A affinity purified.
• Form: Liquid
• Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 135 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
• Recombinant Antibody: Yes