PSMD8 rabbit pAb

CAT: 0855-ES13880-01Size: 50 µLDry Ice: NoHazardous: No
CAT#:0855-ES13880-01Size:50 µL
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Background
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. A pseudogene has been identified on chromosome 1. [provided by RefSeq, Jul 2008]
Description
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. A pseudogene has been identified on chromosome 1. [provided by RefSeq, Jul 2008],
UniProt
P48556
Swiss Prot
P48556
Reactivity
Human; Mouse
Immunogen
Synthesized peptide derived from human PSMD8 AA range: 1-51
Target
PSMD8
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC
Concentration
1 mg/ml
Dilution
WB 1:500-2000; IHC-p 1:50-300
Buffer
-20°C/1 year
Storage Conditions
-20°C/1 year
Fragment
IgG
Subcellular Location
Proteasome complex, nucleus, nucleoplasm, cytosol, proteasome regulatory particle, proteasome regulatory particle, lid subcomplex, proteasome accessory complex, extracellular exosome
Gene ID (Human)
5714

Related Products

CatalogName
ES13882-01PSMD1 rabbit pAb
ES3273-01PSMD2 rabbit pAb
ES6867-01PSMD3 rabbit pAb
ES13881-01PSMD5 rabbit pAb
ES9289-01PSMD9 rabbit pAb
ES4666-01RAB3IP rabbit pAb
ES20751-01Gab1 Rabbit rabbit pAb
ES20703-01JAK2 Rabbit rabbit pAb
ES20758-01ERK1 Rabbit rabbit pAb
ES20599-01VEGF Rabbit rabbit pAb

Alternative Products

CatalogName
MBS8601122-01PSMD8 rabbit pAb
TA322953PSMD8 Rabbit Polyclonal Antibody
GB113140-100Anti-PSMD8 Rabbit pAb
APR26969N-01PSMD8 Rabbit pAb (APR26969N)
YLD6496-01Rabbit anti-PSMD8 Antibody
NBP2-95230-0.1mLRabbit Polyclonal PSMD8 Antibody
331294-01PSMD8

Popular Products