2-Ethynyl-adenosine

• Description:

  2-Ethynyl-labeled adenosine (2-EA) can be used to measure de novo mRNA poly(A) tail synthesis in proliferating cells. 2-EA is cell permeable and incorporates into nascent mRNA transcripts both transcriptionally by RNA polymerase I,II and III and posttranscriptionally by poly(A) polymerase instead of their natural analolg adenosine.

• UNSPSC:

  12352208

• UNSPSC Description:

  Nucleic acids

• HS Code:

  29349990

• eClass Number:

  34160990

• eClass Product Group:

  Nucleinsäure (nicht klassifiziert)

• Applications:

  mRNA poly(A) tail synthesis monitoring[1]

• Purity:

  ≥ 95 % (HPLC)

• Form:

  Solid

• Color:

  White to off-White

• Autoclavability:

  false

• Solubility:

  up to 4.0 mM in 1 x PBS

• Smiles:

  C12c (nc (nc2n (cn1) [C@H]1[C@@H] ([C@@H] ([C@H] (O1) CO) O) O) C#C) N

• Shipping Conditions:

  Shipped at ambient temperature

• Storage Conditions:

  Store at -20 °C. Short term exposure (up to 1 week cumulative) to ambient temperature possible.

• Storage Temperature:

  Store at -20 °C

• Notes:

  Short term exposure (up to 1 week cumulative) to ambient temperature possible.

• Shelf Life:

  12 months after date of delivery