m-PEG10-acid

• UNSPSC Description:

  m-PEG10-acid is a non-cleavable 10 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. m-PEG10-acid is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[2].

• Target Antigen:

  ADC Linker; PROTAC Linkers

• Type:

  ADC Related

• Related Pathways:

  Antibody-drug Conjugate/ADC Related;PROTAC

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/m-peg10-acid.html

• Solubility:

  10 mM in DMSO

• Smiles:

  OC(CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC)=O

• Molecular Weight:

  500.58

• References & Citations:

  [1]John F. Donovan et al. Pegylated prodrugs of phenolic trpv1 agonists. WO2020023794A1.|[2]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

• Shipping Conditions:

  Blue Ice

• Clinical Information:

  No Development Reported

• CAS Number:

  2409969-94-2