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Anti-BAD(Ab-112)

CAT: 0171-Y021062Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0171-Y021062Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform. [provided by RefSeq, Jul 2008]
CAS Number
9007-83-4
Reactivity
Human,Mouse,Rat
Immunogen
This antiserum was produced against synthesized non-phosphopeptide derived from human BAD around the phosphorylation site of serine 112 (H-S-SP-Y-P).
Clonality
Polyclonal
Type
Antibodies-Polyclonal
Applications
WB,IHC
Concentration
1ug/ul
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Buffer
phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Shipping Conditions
Ice Pack
Storage Conditions
This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Specificity
BAD (Ab-112) antibody detects endogenous levels of total BAD protein.
Applications Notes
WB: 1:500~1:1000 IHC: 1:50~1:100

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GTR18085928Anti-BAD (Ab-112)
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