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Anti-Zyxin

CAT: 0171-Y058000Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0171-Y058000Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Focal adhesions are actin-rich structures that enable cells to adhere to the extracellular matrix and at which protein complexes involved in signal transduction assemble. Zyxin is a zinc-binding phosphoprotein that concentrates at focal adhesions and along the actin cytoskeleton. Zyxin has an N-terminal proline-rich domain and three LIM domains in its C-terminal half. The proline-rich domain may interact with SH3 domains of proteins involved in signal transduction pathways while the LIM domains are likely involved in protein-protein binding. Zyxin may function as a messenger in the signal transduction pathway that mediates adhesion-stimulated changes in gene expression and may modulate the cytoskeletal organization of actin bundles. Alternative splicing results in multiple transcript variants that encode the same isoform.
CAS Number
9007-83-4
Reactivity
Human
Immunogen
Synthetic peptide conjugated to KLH
Clonality
Polyclonal
Type
Antibodies-Polyclonal
Applications
WB,ELISA,ICC/IF
Concentration
100ug/100ul
Purity
Protein A purified
Buffer
PBS, pH 7.4 with 0.02% Sodium Azide
Shipping Conditions
Ice Pack
Storage Conditions
This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Fragment
Rabbit IgG
Specificity
Not tested with other proteins
Applications Notes
Recommended dilutions Peptide ELISA: 1:32,000 IF: 1/50. WB: 1/500 - 1/1000. Not yet tested in other applications. Optimal dilutions/concentrations should be determined by the end user

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