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Anti-Stat2 (Ab-690)

CAT: 0171-Y021536Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0171-Y021536Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. In response to interferon (IFN), this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 (ISGF3G), in which this protein acts as a transactivator, but lacks the ability to bind DNA directly. Transcription adaptor P300/CBP (EP300/CREBBP) has been shown to interact specifically with this protein, which is thought to be involved in the process of blocking IFN-alpha response by adenovirus. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010]
CAS Number
9007-83-4
Reactivity
Human
Immunogen
The antibody was produced against synthesized non-phosphopeptide derived from human stat2 around the phosphorylation site of tyrosine 690 (R-K-YP-L-K).
Clonality
Polyclonal
Type
Antibodies-Polyclonal
Applications
WB,IHC
Concentration
100ug/100ul
Purity
Affinity purified
Buffer
Rabbit IgG in phosphate buffered saline (without Mg<sup>2</sup>+and Ca<sup>2</sup>+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Shipping Conditions
Ice Pack
Storage Conditions
This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Fragment
IgG
Specificity
Stat2 (Ab-690) Antibody detects endogenous levels of total Stat2 protein.
Applications Notes
WB: 1:500~1:1000 IHC:1:50~1:100