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Anti-Smad3 (Ab-425)

CAT: 0171-Y021325Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0171-Y021325Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions as a transcriptional modulator activated by transforming growth factor-beta and is thought to play a role in the regulation of carcinogenesis. [provided by RefSeq, Apr 2009]
CAS Number
9007-83-4
Reactivity
Human,Mouse,Rat
Immunogen
The antibody was produced against synthesized non-phosphopeptide derived from human Smad3 around the phosphorylation site of serine 425 (C-S-S-V-SP).
Clonality
Polyclonal
Type
Antibodies-Polyclonal
Applications
IHC,IP
Concentration
100ug/100ul
Purity
Affinity purified
Buffer
Rabbit IgG in phosphate buffered saline (without Mg<sup>2</sup>+ and Ca<sup>2</sup>+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Shipping Conditions
Ice Pack
Storage Conditions
This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Fragment
IgG
Specificity
Smad3 (Ab-425) Antibody detects endogenous levels of total Smad3 protein.
Applications Notes
IHC: 1:50~1:100 IF:1:100~1:200

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